Yes, you can take folic acid on an empty stomach, and in fact, it can be more effective.
Here's why:
Folic acid absorption differs based on whether it's from food or a supplement:
- Food Folate: Naturally occurring folate from food has a lower absorption rate, estimated at around 50%.
- Folic Acid Supplements: Folic acid, the synthetic form, boasts a higher absorption rate. When taken with food, about 85% is absorbed. However, when taken on an empty stomach, absorption can reach nearly 100%.
Key Takeaway:
Taking folic acid as a supplement on an empty stomach optimizes its absorption, maximizing its benefits. However, if you experience any stomach upset or discomfort, you can take it with food.