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What is Slough Made Of?

Published in Wound Healing 1 min read

Slough is primarily composed of dead tissue, cellular debris from inflammation, and proteinaceous material.

Slough is a layer of dead tissue that often appears on the surface of wounds. It's a natural byproduct of the body's inflammatory response and healing process. Understanding its composition can help in appropriate wound management.

Components of Slough:

  • Fibrin: A protein involved in blood clotting, forming a network in the slough.
  • White Blood Cells: Immune cells that migrate to the wound site to combat infection and remove debris.
  • Bacteria and Debris: Microorganisms and other foreign materials present in the wound.
  • Dead Tissue: Necrotic cells and tissue that have died due to injury or infection.
  • Proteinaceous Material: A mixture of proteins, including enzymes and structural components of cells.

Slough is essentially the remnants of the inflammatory and repair processes. It is a mixture of components that work together to help the body heal, but its presence can sometimes hinder wound closure. Proper wound care aims to remove slough and promote the growth of healthy tissue.

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